Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

S M Hsu, Laurence Raine, Herbert Fanger · Journal of Histochemistry & Cytochemistry · 1981 · 14.3K citations · Full text

Life Sciences, Immunology, Immunopathology +8

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system.

J K Boyles, Robert E. Pitas, Elaine V. Wilson et al. · Journal of Clinical Investigation · 1985 · 829 citations · Full text

Medicine, Neurobiology, Neuroscience +11

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

Robert E. Pitas, J K Boyles, S H Lee et al. · Journal of Biological Chemistry · 1987 · 710 citations · Full text

Life Sciences, Neurobiology, Neuroscience +12

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

Robert E. Pitas, J K Boyles, Susan H. Lee et al. · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1987 · 694 citations

Life Sciences, Biochemistry, Neuroscience +11

Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets.

Nabil A. Elshourbagy, Warren S.‐L. Liao, Robert W. Mahley et al. · Proceedings of the National Academy of Sciences · 1985 · 508 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +5