D. E. Schmechel

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter et al. · Science · 1993 · 9.5K citations

Life Sciences, Genetics, Neurology +17

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

Warren J. Strittmatter, Ann M. Saunders, D. E. Schmechel et al. · Proceedings of the National Academy of Sciences · 1993 · 4.3K citations · Full text

Life Sciences, Genetics, Neurology +17

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

Ann M. Saunders, Warren J. Strittmatter, D. E. Schmechel et al. · Neurology · 1993 · 3.8K citations · Full text

Life Sciences, Genetics, Neurology +17

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

Elizabeth H. Corder, Ann M. Saunders, Neil Risch et al. · Nature Genetics · 1994 · 1.9K citations

Medicine, Genetics, Neurology +16

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.

D. E. Schmechel, Ann M. Saunders, Warren J. Strittmatter et al. · Proceedings of the National Academy of Sciences · 1993 · 1.5K citations · Full text

Life Sciences, Genetics, Neuroscience +17