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Design and characterization of bivalent Smac-based peptides as antagonists of XIAP and development and validation of a fluorescence polarization assay for XIAP containing both BIR2 and BIR3 domains

Bir3 DomainsBivalent Smac-based PeptidesBiochemistryMedicinePeptide EngineeringBioanalysisPeptide LibraryFluorescence Polarization AssayPeptide SynthesisPharmacologyDrug Discovery