Exogenous Alanine and/or Glucose plus Kanamycin Kills Antibiotic-Resistant Bacteria

Bo Peng, Yubin Su, Hui Li, +4

Cell Metabolism

AntibioticsMedicineAntimicrobial TherapyMicrobiologyAntimicrobial Chemotherapy +4

A Potent and Orally Active Antagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment

Qian Cai, Haiying Sun, Yuefeng Peng, +14

Journal of Medicinal Chemistry

Design of Triazole-Stapled BCL9 α-Helical Peptides to Target the β-Catenin/B-Cell CLL/lymphoma 9 (BCL9) Protein–Protein Interaction

Steven A. Kawamoto, Adriana Coleska, Ran Xu, +3

Journal of Medicinal Chemistry

Peptide EngineeringImmunologyMolecular BiologyPeptide ScienceClick Chemistry +17

Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein

Haibin Zhou, Longchuan Bai, Renqi Xu, +16

Journal of Medicinal Chemistry

Stat3 Sh2 DomainProtein AssemblyMolecular BiologyCancer BiologyTumor Biology +20

SM-164: A Novel, Bivalent Smac Mimetic That Induces Apoptosis and Tumor Regression by Concurrent Removal of the Blockade of cIAP-1/2 and XIAP

Jianfeng Lü, Longchuan Bai, Haiying Sun, +10

Cancer Research

Tumor RegressionApoptosis ProteinApoptosisImmunologyCell Death +16

Dual Vascular Endothelial Growth Factor Receptor and Fibroblast Growth Factor Receptor Inhibition Elicits Antitumor Immunity and Enhances Programmed Cell Death-1 Checkpoint Blockade in Hepatocellular Carcinoma

Haijing Deng, Anna Kan, Ning Lyu, +12

Liver Cancer

Fructose Restores Susceptibility of Multidrug-Resistant <i>Edwardsiella tarda</i> to Kanamycin

Yubin Su, Bo Peng, Yi Han, +2

Journal of Proteome Research

Synthesis and adsorption performance of La@ZIF-8 composite metal–organic frameworks

Junqi Li, Haizhou Chang, Yuhao Li, +4

RSC Advances

Structure-Based Design of Conformationally Constrained, Cell-Permeable STAT3 Inhibitors

Jianyong Chen, Longchuan Bai, Denzil Bernard, +5

ACS Medicinal Chemistry Letters

Drug TargetDrug TargetingMedicineNatural SciencesSmall Molecules +13

IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance

Yi Han, Yanyu Zhang, Yi‐Qian Pan, +12

Molecular Cell

InflammationCytokineCancer ImmunosurveillanceIron-sulfur Cluster MaintenanceIron Metabolism +9