Concepedia

Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9

Lorraine A. O’Reilly, Paul G. Ekert, Natasha L. Harvey, Vanessa S. Marsden, L Cullen, David L. Vaux, Georg Häcker, Carina Magnusson, Miha Pakusch, Francesco Cecconi,

Cell Death and Differentiation · 2002 · 191 citations · 38 references

DOI

Concepts

References

38

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.3K citations · Full text

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Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3

Hua Zou, William J. Henzel, Xuesong Liu et al. · Cell · 1997 · 3.1K citations · Full text

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FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

Marta Muzio, Arul M. Chinnaiyan, Frank Kischkel et al. · Cell · 1996 · 3.1K citations · Full text

, , +14

FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

Arul M. Chinnaiyan, Karen O’Rourke, Muneesh Tewari et al. · Cell · 1995 · 2.4K citations · Full text

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Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death

Mark Boldin, Tanya Goncharov, Yury V Goltseve et al. · Cell · 1996 · 2.3K citations · Full text

, , +12