Episomal vectors to monitor and induce somatic hypermutation in human Burkitt-Lymphoma cell lines

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

Riccardo Dalla‐Favera, Marco Bregni, J Erikson et al. · Proceedings of the National Academy of Sciences · 1982 · 1.8K citations

Complete Gene, Genetics, Immunology +16

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.

Rebecca Taub, Ilan R. Kirsch, Cynthia C. Morton et al. · Proceedings of the National Academy of Sciences · 1982 · 1.4K citations · Full text

Lymphoid Neoplasia, Immunogenetics, Xenotransplantation +14

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

Laura Pasqualucci, Peter Neumeister, Tina Goossens et al. · Nature · 2001 · 1K citations

Lymphoid Neoplasia, Multiple Proto-oncogenes, Pathology +4

Requirement of the Activation-Induced Deaminase ( <i>AID</i> ) Gene for Immunoglobulin Gene Conversion

Hiroshi Arakawa, Jessica Hauschild, Jean-Marie Buerstedde · Science · 2002 · 468 citations

Immunodeficiencies, Genetics, Immunology +16

AID Is Required for c-myc/IgH Chromosome Translocations In Vivo

Almudena R. Ramiro, Mila Janković, Thomas Eisenreich et al. · Cell · 2004 · 453 citations · Full text

Histocompatibility, Chromatin, C-myc/igh Chromosome Translocations +4