Concepedia

Episomal Vector Maintenance

Episomal Vector Maintenance is a molecular biology technique that enables the stable replication and inheritance of non-integrating plasmid-based DNA constructs in host cells through autonomous extrachromosomal replication regulated by specific origin of replication elements.

81

Publications

4K

Citations

353

Authors

112

Institutions

Publications per year

2017–2026

4

Parents

Publications

81

Episomal Vectors Rapidly and Stably Produce High-Titer Recombinant Retrovirus

Todd M. Kinsella, Garry P. Nolan · Human Gene Therapy · 1996 · 743 citations

, , +14

A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells

Christoph Piechaczek, Christiane Fetzer, Armin Baiker et al. · Nucleic Acids Research · 1999 · 211 citations · Full text

, , +14

Nuclear scaffold/matrix attached region modules linked to a transcription unit are sufficient for replication and maintenance of a mammalian episome

Andreas Jenke, Isa M. Stehle, Frank Herrmann et al. · Proceedings of the National Academy of Sciences · 2004 · 155 citations · Full text

, , +17

Epstein-Barr virus shuttle vector for stable episomal replication of cDNA expression libraries in human cells.

Robert F. Margolskee, Paula Kavathas, Paul Berg · Molecular and Cellular Biology · 1988 · 152 citations · Full text

, , +17

Mitotic stability of an episomal vector containing a human scaffold/matrix-attached region is provided by association with nuclear matrix

Alfons Baiker, Christian Maercker, Christoph Piechaczek et al. · Nature Cell Biology · 2000 · 141 citations

, , +14

1–5 of 81

Authors

353

  1. HJ
    Hans J. Lipps

    Witten/Herdecke University, Germany

    7 publications · 642 citations

    7

    h-index

  2. TW
    Tianyun Wang

    Henan Medical University, China

    4 publications · 85 citations

    4

    h-index

  3. AA
    Aglaia Athanassiadou

    University of Patras, Greece

    3 publications · 135 citations

    3

    h-index

  4. JH
    Jean‐Michel H. Vos

    University of North Carolina at Chapel Hill, United States

    3 publications · 140 citations

    3

    h-index

  5. JB
    Juergen Bode

    Helmholtz Centre for Infection Research, Germany

    3 publications · 365 citations

    3

    h-index

1–5 of 353

Institutions

112

  1. Witten/Herdecke University

    Witten, Germany

    7 h-index

    22 publications

    2.4K citations

  2. Stanford University

    Stanford, United States

    7 h-index

    16 publications

    1.8K citations

  3. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    5 h-index

    10 publications

    460 citations

  4. Henan Medical University

    Xinxiang, China

    4 h-index

    19 publications

    440 citations

  5. University of Ferrara

    Ferrara, Italy

    3 h-index

    10 publications

    421 citations

  6. University of Patras

    Pátrai, Greece

    3 h-index

    9 publications

    289 citations

  7. Helmholtz Centre for Infection Research

    Braunschweig, Germany

    3 h-index

    13 publications

    2.2K citations

  8. The Wistar Institute

    Philadelphia, United States

    3 h-index

    11 publications

    572 citations

1–8 of 112

Venues

  1. Gene

    6 publications · 196 citations

    6

    h-index

  2. Molecular and Cellular Biology

    MCB · 6 publications · 307 citations

    6

    h-index

  3. Gene Therapy

    5 publications · 224 citations

    5

    h-index

  4. PubMed

    Repository · 5 publications · 152 citations

    5

    h-index

  5. Human Gene Therapy

    5 publications · 857 citations

    5

    h-index

1–5