Alternative splicing of the ErbB-4 cytoplasmic domain and its regulation by hedgehog signaling identify distinct medulloblastoma subsets

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Jussi Taipale, James Chen, Michael K. Cooper et al. · Nature · 2000 · 1.3K citations

Medicine, Cancer Biology, Oncology +9

γ-Secretase Cleavage and Nuclear Localization of ErbB-4 Receptor Tyrosine Kinase

Chang-Yuan Ni, M. Paul Murphy, Todd E. Golde et al. · Science · 2001 · 858 citations

Life Sciences, Biochemistry, Molecular Biology +14

Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

Heidi Hahn, Leszek Wojnowski, Anne M. Zimmer et al. · Nature Medicine · 1998 · 451 citations

Medicine, Oncology, Pathology +15

Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4

Dongxiao Zhang, Mark X. Sliwkowski, Melanie R. Mark et al. · Proceedings of the National Academy of Sciences · 1997 · 390 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +10

Clinical, Histopathologic, and Molecular Markers of Prognosis: Toward a New Disease Risk Stratification System for Medulloblastoma

Amar Gajjar, Roberto Hernán, Mehmet Koçak et al. · Journal of Clinical Oncology · 2004 · 281 citations · Full text

Medicine, Oncology, Pathology +17