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Determinants for degradation of SAMHD1, Mus81 and induction of G2 arrest in HIV-1 Vpr and SIVagm Vpr

Ana Beatriz DePaula-Silva, Patrick A Cassiday, Jeffrey Chumley, Alberto Bosque, Carlos MR Monteiro-Filho, Cathal Mahon, Kelsey R. Cone, Nevan J. Krogan, Nels C. Elde, Vicente Planelles

Virology · 2015 · 13 citations · 30 references

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30

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Teresa A. Soucy, Peter G. Smith, Michael A. Milhollen et al. · Nature · 2009 · 2K citations

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SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

Nadine Laguette, Bijan Sobhian, Nicoletta Casartelli et al. · Nature · 2011 · 1.5K citations

, , +12

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

Kasia Hrecka, Caili Hao, Magda Gierszewska et al. · Nature · 2011 · 1.2K citations

, , +9

Epoxomicin, a potent and selective proteasome inhibitor, exhibits <i>in vivo</i> antiinflammatory activity

Lihao Meng, Royce Mohan, Benjamin H. Kwok et al. · Proceedings of the National Academy of Sciences · 1999 · 933 citations

, , +15

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

Julian He, S Choe, Robert Walker et al. · Journal of Virology · 1995 · 918 citations · Full text

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