Concepedia

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

Kasia Hrecka, Caili Hao, Magda Gierszewska, Selene K. Swanson, Małgorzata Kęsik-Brodacka, Smita Srivastava, Laurence Florens, Michael P. Washburn, Jacek Skowroński

Nature · 2011 · 1.2K citations · 26 references

DOI

Concepts

References

26

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

Luigi Naldini, Ulrike Blömer, Philippe Gallay et al. · Science · 1996 · 4.9K citations

, , +14

A quantitative assay for HIV DNA integration in vivo

Scott L. Butler, Mark S. Hansen, Frederic D. Bushman · Nature Medicine · 2001 · 702 citations

, , +12

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

Gillian Rice, Jacquelyn Bond, Aruna Asipu et al. · Nature Genetics · 2009 · 684 citations

, , +11

Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery

Stéphane Angers, Ti Li, Xianhua Yi et al. · Nature · 2006 · 667 citations

, , +12

Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease

Yun‐Gui Yang, Tomas Lindahl, Deborah E. Barnes · Cell · 2007 · 581 citations · Full text

, , +16