Concepedia

G2 Checkpoint Arrest

G2 Checkpoint Arrest is a cell-cycle arrest mechanism that halts progression from the G2 phase to mitosis in response to DNA damage or incomplete replication, ensuring genomic stability before cell division.

577

Publications

44K

Citations

3K

Authors

839

Institutions

Publications per year

2017–2026

77

Variants

G2/m Checkpoint Arrest

Parents

Publications

577

Requirement for p53 and p21 to Sustain G <sub>2</sub> Arrest After DNA Damage

Fred Bunz, Annie Dutriaux, Christoph Lengauer et al. · Science · 1998 · 2.8K citations

, , +17

Mitotic and G <sub>2</sub> Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

Cheng‐Yuan Peng, Paul R. Graves, Richard S. Thoma et al. · Science · 1997 · 1.3K citations

, , +17

Chk2/hCds1 functions as a DNA damage checkpoint in G<sub>1</sub>by stabilizing p53

Nabil Chehab, Asra Malikzay, Michael Appel et al. · Genes & Development · 2000 · 792 citations · Full text

, , +17

Saccharomyces Ku70, Mre11/Rad50, and RPA Proteins Regulate Adaptation to G2/M Arrest after DNA Damage

J. Kent Moore, Allyson Holmes, Keiko Umezu et al. · Cell · 1998 · 777 citations · Full text

, , +15

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.

Ted Weinert, Gretchen Kiser, Leland H. Hartwell · Genes & Development · 1994 · 748 citations · Full text

, , +17

1–5 of 577

Authors

3K

  1. MJ
    Matthew J. O’Connell

    Icahn School of Medicine at Mount Sinai, United States

    12 publications · 1.1K citations

    12

    h-index

  2. WK
    William K. Kaufmann

    University of North Carolina at Chapel Hill, United States

    11 publications · 620 citations

    11

    h-index

  3. MR
    Michel Roberge

    University of British Columbia, Canada

    11 publications · 451 citations

    10

    h-index

  4. RS
    Richard S. Paules

    National Institute of Environmental Health Sciences, United States

    9 publications · 502 citations

    9

    h-index

  5. RJ
    Raymond J. Andersen

    University of British Columbia, Canada

    9 publications · 447 citations

    9

    h-index

1–5 of 3K

Institutions

839

  1. National Cancer Institute

    Bethesda, United States

    17 h-index

    72 publications

    11K citations

  2. National Institutes of Health

    Bethesda, United States

    16 h-index

    67 publications

    9.7K citations

  3. University of British Columbia

    Vancouver, Canada

    13 h-index

    55 publications

    2.8K citations

  4. Inserm

    Paris, France

    13 h-index

    44 publications

    2.6K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    12 h-index

    45 publications

    2.9K citations

  6. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    11 h-index

    31 publications

    1.7K citations

  7. University of Pennsylvania

    Philadelphia, United States

    10 h-index

    30 publications

    3.7K citations

  8. Harvard University

    Cambridge, United States

    10 h-index

    14 publications

    578 citations

1–8 of 839

Venues

  1. PubMed

    Repository · 43 publications · 3.7K citations

    29

    h-index

  2. Journal of Biological Chemistry

    JBC · 36 publications · 3K citations

    29

    h-index

  3. Oncogene

    21 publications · 1.4K citations

    21

    h-index

  4. Molecular and Cellular Biology

    MCB · 23 publications · 2.7K citations

    20

    h-index

  5. Cell Cycle

    27 publications · 966 citations

    18

    h-index

1–5