Regulatory evolution of innate immunity through co-option of endogenous retroviruses

Edward B. Chuong, Nels C. Elde, Cédric Feschotte

Science

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote

Jonathan A. Eisen, Robert S. Coyne, Martin Wu, +49

PLoS Biology

Ciliate Tetrahymena ThermophilaFunctional DiversityGeneticsMolecular BiologyMolecular Genetics +23

Poxviruses Deploy Genomic Accordions to Adapt Rapidly against Host Antiviral Defenses

Nels C. Elde, Stephanie J. Child, Michael T. Eickbush, +5

Cell

Viral EvolutionMolecular VirologyPathogenesisAdapt RapidlyVirology +5

Protein kinase R reveals an evolutionary model for defeating viral mimicry

Nels C. Elde, Stephanie J. Child, Adam P. Geballe, +1

Nature

Viral ReplicationViral EvolutionMolecular VirologyPathogenesisMolecular Biology +7

cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection

Megan H. Orzalli, Nicole M. Broekema, Benjamin A. Diner, +4

Proceedings of the National Academy of Sciences

Escape from bacterial iron piracy through rapid evolution of transferrin

Matthew F. Barber, Nels C. Elde

Science

BacteriologyInnate ImmunityBacterial PathogensHost ResponseBacterial Iron Piracy +17

Wham: Identifying Structural Variants of Biological Consequence

Zev Kronenberg, Edward J. Osborne, Kelsey R. Cone, +5

PLoS Computational Biology

Elucidation of Clathrin-Mediated Endocytosis in Tetrahymena Reveals an Evolutionarily Convergent Recruitment of Dynamin

Nels C. Elde, Garry Morgan, Mark Winey, +2

PLoS Genetics

Molecular BiologyCytoskeletonCell Biological ComplexityCellular PhysiologyTetrahymena Reveals +14

Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape

Dustin C. Hancks, Melissa K. Hartley, Celia Hagan, +2

PLoS Genetics

Viral ReplicationGeneticsMolecular BiologyNucleic Acid Amplification TestMolecular Genetics +24

DisAp-dependent striated fiber elongation is required to organize ciliary arrays

Domenico F. Galati, Stephanie Bonney, Zev Kronenberg, +7

The Journal of Cell Biology