Megan H. Orzalli

Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein

Megan H. Orzalli, Neal A. DeLuca, David M. Knipe · Proceedings of the National Academy of Sciences · 2012 · 415 citations · Full text

cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection

Megan H. Orzalli, Nicole M. Broekema, Benjamin A. Diner et al. · Proceedings of the National Academy of Sciences · 2015 · 248 citations · Full text

A Promiscuous Lipid-Binding Protein Diversifies the Subcellular Sites of Toll-like Receptor Signal Transduction

Kevin S. Bonham, Megan H. Orzalli, Kachiko Hayashi et al. · Cell · 2014 · 217 citations · Full text

Inflammation, Toll-like Receptors, Proteinlipid Interaction +10

Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation

Carina C. de Oliveira Mann, Megan H. Orzalli, David S. King et al. · Cell Reports · 2019 · 204 citations · Full text

Innate Immune System, Immune Regulation, Immunology +25

Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA

Megan H. Orzalli, Sara E. Conwell, Christian Berrios et al. · Proceedings of the National Academy of Sciences · 2013 · 175 citations · Full text