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BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib

Isabella Faraoni, Mirco Compagnone, Serena Lavorgna, Daniela F. Angelini, Maria Teresa Cencioni, Eleonora Piras, Paola Panetta, Tiziana Ottone, Susanna Dolci, Adriano Venditti,

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2014 · 62 citations · 43 references

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43

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Hannah Farmer, Nuala McCabe, Christopher J. Lord et al. · Nature · 2005 · 6.7K citations

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DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

Emmy P. Rogakou, Duane R. Pilch, Ann H. Orr et al. · Journal of Biological Chemistry · 1998 · 5.4K citations · Full text

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Helen E. Bryant, Niklas Schultz, Huw D. Thomas et al. · Nature · 2005 · 5.2K citations

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Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

New England Journal of Medicine · 2013 · 5.2K citations · Full text

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Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from <i>BRCA</i> Mutation Carriers

Peter C.C. Fong, David S. Boss, Timothy A. Yap et al. · New England Journal of Medicine · 2009 · 3.6K citations · Full text

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