Concepedia

An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope

Ulrike Seifert, Concepción Marañón, Ayelet Shmueli, Jean-François Desoutter, Lisa M. Wesoloski, Katharina Janek, Peter Henklein, Susanne Diescher, Muriel Andrieu, Henri de la Salle,

Nature Immunology · 2003 · 227 citations · 31 references

DOI

Concepts

References

31

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein et al. · Cell · 1994 · 2.5K citations

, , +14

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

Thomas Serwold, Federico Gonzãlez, Jennifer Kim et al. · Nature · 2002 · 620 citations

, , +12

An IFN-γ–induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I–presented peptides

Tomo Šarić, Shih‐Chung Chang, Akira Hattori et al. · Nature Immunology · 2002 · 529 citations

, , +13

A Giant Protease with Potential to Substitute for Some Functions of the Proteasome

Elke Geier, Günter Pfeifer, Matthias Wilm et al. · Science · 1999 · 372 citations

, , +16

Homozygous Human TAP Peptide Transporter Mutation in HLA Class I Deficiency

Henri de la Salle, Daniel Hanau, Dominique Fricker et al. · Science · 1994 · 349 citations

, , +17