Concepedia

tert-Butylhydroquinone (tBHQ) protects hepatocytes against lipotoxicity via inducing autophagy independently of Nrf2 activation

Songtao Li, Jiaxin Li, Chen Shen, Ximei Zhang, Shan Sun, Michael Cho, Changhao Sun, Zhenyuan Song

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2013 · 88 citations · 48 references

DOIFull text

Open access

Concepts

References

48

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim, Mondira Kundu, Benoı̂t Viollet et al. · Nature Cell Biology · 2011 · 6.8K citations · Full text

, , +10

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Yukihiro Kabeya · The EMBO Journal · 2000 · 6.5K citations · Full text

, , +9

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

Ken Itoh, Tomoki Chiba, Satoru Takahashi et al. · Biochemical and Biophysical Research Communications · 1997 · 3.9K citations

, , +10

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh et al. · Genes & Development · 1999 · 3.5K citations · Full text

, , +18

Dissection of the Autophagosome Maturation Process by a Novel Reporter Protein, Tandem Fluorescent-Tagged LC3

Shunsuke Kimura, Takeshi Noda, Tamotsu Yoshimori · Autophagy · 2007 · 2.2K citations · Full text

, , +17