The structure of a serpin–protease complex revealed by intramolecular distance measurements using donor–donor energy migration and mapping of interaction sites

The serpin superfamily of proteinase inhibitors: structure, function, and regulation.

Jan Potempa, Edward Korzus, James Travis · Journal of Biological Chemistry · 1994 · 875 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Human α1-proteinase inhibitor

Hartmut Loebermann, R. Tokuoka, J. Deisenhofer et al. · Journal of Molecular Biology · 1984 · 772 citations

Structural basis of latency in plasminogen activator inhibitor-1

James Mottonen, Arne Strand, J. Symerský et al. · Nature · 1992 · 553 citations

Life Sciences, Biochemistry, Molecular Biology +11

Serpin-Protease Complexes Are Trapped as Stable Acyl-Enzyme Intermediates

Daniel A. Lawrence, David Ginsburg, Duane E. Day et al. · Journal of Biological Chemistry · 1995 · 247 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Formation of the covalent serpin-proteinase complex involves translocation of the proteinase by more than 70 Å and full insertion of the reactive center loop into β-sheet A

Efstratios Stratikos, Peter G.W. Gettins · Proceedings of the National Academy of Sciences · 1999 · 213 citations

Life Sciences, Biochemistry, Molecular Biology +17