Efstratios Stratikos

Formation of the covalent serpin-proteinase complex involves translocation of the proteinase by more than 70 Å and full insertion of the reactive center loop into β-sheet A

Efstratios Stratikos, Peter G.W. Gettins · Proceedings of the National Academy of Sciences · 1999 · 213 citations

Life Sciences, Biochemistry, Molecular Biology +17

Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1

Tina Nguyen, Shih‐Chung Chang, Irini Evnouchidou et al. · Nature Structural & Molecular Biology · 2011 · 203 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Human cytomegalovirus microRNA miR-US4-1 inhibits CD8+ T cell responses by targeting the aminopeptidase ERAP1

Sungchul Kim, Sanghyun Lee, Jinwook Shin et al. · Nature Immunology · 2011 · 178 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Cutting Edge: Coding Single Nucleotide Polymorphisms of Endoplasmic Reticulum Aminopeptidase 1 Can Affect Antigenic Peptide Generation In Vitro by Influencing Basic Enzymatic Properties of the Enzyme

Irini Evnouchidou, Ram P. Kamal, Sergey S. Seregin et al. · The Journal of Immunology · 2011 · 137 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses

Efthalia Zervoudi, Emmanuel Saridakis, James R. Birtley et al. · Proceedings of the National Academy of Sciences · 2013 · 128 citations · Full text

Life Sciences, Immunology, Oncology +15