Pure dietary flavonoids quercetin and (−)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men

Wine, alcohol, platelets, and the French paradox for coronary heart disease

S. Renaud, M. de Lorgeril · The Lancet · 1992 · 3.6K citations

Medicine, Cardiology, Clinical Cardiology +13

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.

Jonathan S. Stamler, Daniel I. Simon, John A. Osborne et al. · Proceedings of the National Academy of Sciences · 1992 · 1.5K citations

Life Sciences, Biochemistry, Molecular Biology +13

Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.

Jonathan S. Stamler, O Jaraki, Jason W. Osborne et al. · Proceedings of the National Academy of Sciences · 1992 · 1.2K citations · Full text

Life Sciences, Biochemistry, Physiology +14

(–)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans

Hagen Schroeter, Jan C. Balzer, Petra Kleinbongard et al. · Proceedings of the National Academy of Sciences · 2006 · 1K citations

Life Sciences, Nutrition, Nutritional Sciences +16

Plasma nitrite rather than nitrate reflects regional endothelial nitric oxide synthase activity but lacks intrinsic vasodilator action

Thomas E. Lauer, Michael Preik, Tienush Rassaf et al. · Proceedings of the National Academy of Sciences · 2001 · 589 citations · Full text

Medicine, Pharmacology, Physiology +9