Concepedia

Stability and activity of MCSP-specific chimeric antigen receptors (CARs) depend on the scFv antigen-binding domain and the protein backbone

Christian Krug, Katrin Birkholz, Alexander Paulus, Michael Schwenkert, Patrick Schmidt, Nicole Hoffmann, Andreas Hombach, Georg H. Fey, Hinrich Abken, Gerold Schuler,

Cancer Immunology Immunotherapy · 2015 · 52 citations · 57 references

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57

Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2

Richard A. Morgan, James C. Yang, Mio Kitano et al. · Molecular Therapy · 2010 · 2.5K citations · Full text

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T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia

Michael Kalos, Bruce L. Levine, David L. Porter et al. · Science Translational Medicine · 2011 · 2.4K citations · Full text

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Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

Michael C. Milone, Jonathan D. Fish, Carmine Carpenito et al. · Molecular Therapy · 2009 · 1.2K citations · Full text

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Mesothelin-Specific Chimeric Antigen Receptor mRNA-Engineered T Cells Induce Antitumor Activity in Solid Malignancies

Gregory L. Beatty, Andrew R. Haas, Marcela V. Maus et al. · Cancer Immunology Research · 2013 · 860 citations · Full text

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T Cells Expressing Chimeric Antigen Receptors Can Cause Anaphylaxis in Humans

Marcela V. Maus, Andrew R. Haas, Gregory L. Beatty et al. · Cancer Immunology Research · 2013 · 592 citations · Full text

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