Concepedia

Potent Inhibition of Cytochrome P-450 2D6-Mediated DextromethorphanO-Demethylation by Terbinafine

Susan M. Abdel‐Rahman, Kenda Marcucci, Thomas C. Boge, Russell Gotschall, Gregory L. Kearns, J. Steven Leeder

Drug Metabolism and Disposition · 1999 · 57 citations · 21 references

DOI

Concepts

References

21

Polymorphic dextromethorphan metabolism: Co-segregation of oxidative O-demethylation with debrisoquin hydroxylation

B. Schmid, J Bircher, R Preisig et al. · Clinical Pharmacology & Therapeutics · 1985 · 387 citations

, , +12

Effect of common organic solvents on in vitro cytochrome P450-mediated metabolic activities in human liver microsomes.

Nathalie Chauret, Annick Gauthier, Deborah A. Nicoll‐Griffith · PubMed · 1998 · 310 citations

, , +16

Clinical significance of the sparteine/debrisoquine oxidation polymorphism

K. Br�sen, L. F. Gram · European Journal of Clinical Pharmacology · 1989 · 285 citations

, , +6

Effects of Freezing, Thawing, and Storing Human Liver Microsomes on Cytochrome P450 Activity

Robin E. Pearce, Christin J. McIntyre, Ajay Madan et al. · Archives of Biochemistry and Biophysics · 1996 · 253 citations

, , +13

Evaluation of the selectivity of In vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities.

Dean Hickman, Ji Ping Wang, Yi Wang et al. · PubMed · 1998 · 223 citations

, , +17