Clinical significance of the sparteine/debrisoquine oxidation polymorphism

POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN

A. Mahgoub, L. G. Dring, Jeffrey R. Idle et al. · The Lancet · 1977 · 1.2K citations

Pharmacy, Biochemistry, Pharmacology +6

The P450 Gene Superfamily: Recommended Nomenclature

Daniel W. Nebert, Milton Adesnik, Minor J. Coon et al. · DNA · 1987 · 815 citations

Life Sciences, Genetics, Molecular Genetics +15

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

Frank J. Gonzalez, Radek C. Skodat, Shioko Kimura et al. · Nature · 1988 · 718 citations

Life Sciences, Genetics, Molecular Genetics +12

Defective N-oxidation of sparteine in man: A new pharmacogenetic defect

Michel Eichelbaum, N. Spannbrucker, Barbara Steincke et al. · European Journal of Clinical Pharmacology · 1979 · 635 citations

Medicine, Molecular Medicine, Pharmacology +8

Cloning of the cDNA for the human beta 1-adrenergic receptor.

Thomas Frielle, Sheila Collins, Kiefer W. Daniel et al. · Proceedings of the National Academy of Sciences · 1987 · 580 citations · Full text

Life Sciences, Genetics, Molecular Biology +11