Thomas Frielle

Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin

Richard A. F. Dixon, Brian K. Kobilka, David J. Strader et al. · Nature · 1986 · 1.3K citations

Life Sciences, Biochemistry, Pharmacology +8

cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.

Brian K. Kobilka, Richard A. F. Dixon, Thomas Frielle et al. · Proceedings of the National Academy of Sciences · 1987 · 683 citations · Full text

Life Sciences, Genetics, Molecular Biology +11

Cloning of the cDNA for the human beta 1-adrenergic receptor.

Thomas Frielle, Sheila Collins, Kiefer W. Daniel et al. · Proceedings of the National Academy of Sciences · 1987 · 580 citations · Full text

Life Sciences, Genetics, Molecular Biology +11

An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins

Brian K. Kobilka, Thomas Frielle, Sheila Collins et al. · Nature · 1987 · 512 citations

Life Sciences, Genetics, Molecular Genetics +13

Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions.

Brian K. Kobilka, Thomas Frielle, Henrik Dohlman et al. · Journal of Biological Chemistry · 1987 · 246 citations · Full text

Medicine, Genetics, Molecular Genetics +7