PubMed · 1996 · 60 citations · 0 references
Life SciencesPharmacologyPlant SciencesInnate ImmunityPlant BiochemistryComplement RegulationComplement SystemComplement System PharmacologyMedicinal PlantsComplement System ActivationComplement System ModulationFlavonoid GlycosidesPlant Phenolics
From extracts of olive (Olea europaea L., Oleaceae) leaves showing anti-complementary activity, the flavonoids apigenin, apigenin-4'-O-rhamnosylglucoside, apigenin-7-O-glucoside, luteolin, luteolin-4'-O-glucoside, luteolin-7-O-glucoside, chrysoeriol, chrysoeriol-7-O-glucoside and quercetin-3-O-rhamnoside were isolated. Major isolated constituents strongly inhibited the classical pathway of the complement system.