Concepedia

BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia

Jae‐Seok Roe, Fatih Mercan, Keith Rivera, Darryl Pappin, Christopher R. Vakoc

Molecular Cell · 2015 · 340 citations · 50 references

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50

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

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MEME SUITE: tools for motif discovery and searching

Timothy L. Bailey, Mikael Bodén, Fabian A. Buske et al. · Nucleic Acids Research · 2009 · 11.5K citations · Full text

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Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud et al. · Nature · 2010 · 4.3K citations · Full text

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BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

Jake Delmore, Ghayas C. Issa, Madeleine E. Lemieux et al. · Cell · 2011 · 2.8K citations · Full text

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Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

Wei Gu, R G Roeder · Cell · 1997 · 2.6K citations · Full text

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