Jae‐Seok Roe

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

Philipp Rathert, Mareike Roth, Tobias Neumann et al. · Nature · 2015 · 517 citations · Full text

Transcriptional Regulation, Lineage Plasticity, Developmental Biology +8

Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis

Jae‐Seok Roe, Chang‐Il Hwang, Tim D.D. Somerville et al. · Cell · 2017 · 467 citations · Full text

Tumor Biology, Pancreatic Cancer, Medicine +3

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated <i>Myc</i> regulation

Junwei Shi, Warren A. Whyte, Cinthya Zepeda‐Mendoza et al. · Genes & Development · 2013 · 450 citations · Full text

Acute Leukemia Maintenance, Genetics, Immunology +19

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance

Nilgun Tasdemir, Ana Banito, Jae‐Seok Roe et al. · Cancer Discovery · 2016 · 385 citations · Full text

BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia

Jae‐Seok Roe, Fatih Mercan, Keith Rivera et al. · Molecular Cell · 2015 · 335 citations · Full text

Hematological Malignancy, Transcriptional Regulation, Hematopoietic Transcription Factors +12