Concepedia

Protective Mechanism of Stabilizing Excipients Against Dehydration in the Freeze-Drying of Proteins

Yonghong Liao, Marc B. Brown, Abdul Quader, Gary P. Martin

Pharmaceutical Research · 2002 · 77 citations · 16 references

DOI

Concepts

References

16

Methods of Enzymatic Analysis

Journal of AOAC INTERNATIONAL · 1975 · 19.9K citations

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Ideal copolymers and the second‐order transitions of synthetic rubbers. i. non‐crystalline copolymers

M. Gordon, James S. Taylor · Journal of Applied Chemistry · 1952 · 2.6K citations

, , +17

Dehydration-induced conformational transitions in proteins and their inhibition by stabilizers

Steven J. Prestrelski, Nicole I. Tedeschi, Tsutomu Arakawa et al. · Biophysical Journal · 1993 · 717 citations · Full text

, , +12

The mechanism of cryoprotection of proteins by solutes

John F. Carpenter, John H. Crowe · Cryobiology · 1988 · 555 citations

, , +7

Hydrogen Bonding between Sugar and Protein Is Responsible for Inhibition of Dehydration-Induced Protein Unfolding

Steven Allison, Byeong S. Chang, Theodore W. Randolph et al. · Archives of Biochemistry and Biophysics · 1999 · 538 citations

, , +14