Concepedia

CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy

Linda Diehl, Annemieke Th. den Boer, Stephen P. Schoenberger, Ellen I. H. van der Voort, Ton N. Schumacher, Cornelis J.M. Melief, Rienk Offringa, René E. M. Toes

Nature Medicine · 1999 · 463 citations · 32 references

DOI

Concepts

References

32

Phenotypic Analysis of Antigen-Specific T Lymphocytes

John D. Altman, Paul Moss, Philip Goulder et al. · Science · 1996 · 3.6K citations

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T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

Stephen P. Schoenberger, René E. M. Toes, Ellen I. H. van der Voort et al. · Nature · 1998 · 2.6K citations

, , +15

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

J P Ridge, Francesca Di Rosa, Polly Matzinger · Nature · 1998 · 2.3K citations

, , +13

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

Sally R.M. Bennett, Freda Karamalis, Richard A. Flavell et al. · Nature · 1998 · 2.1K citations

, , +12

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

Marina Cella, Doris Scheidegger, Kathrin Palmer-Lehmann et al. · The Journal of Experimental Medicine · 1996 · 2K citations · Full text

, , +17