Concepedia

Hybrid chemistry. Part 4: Discovery of etravirine–VRX-480773 hybrids as potent HIV-1 non-nucleoside reverse transcriptase inhibitors

Zheng-Yong Wan, Yuan Tao, Ya-Feng Wang, Tian-Qi Mao, Hong Yin, Fen‐Er Chen, Hu‐Ri Piao, Erik De Clercq, Dirk Daelemans, Christophe Pannecouque

Bioorganic & Medicinal Chemistry · 2015 · 28 citations · 22 references

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22

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

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Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

Rudi Pauwels, Jan Balzarini, Masanori Baba et al. · Journal of Virological Methods · 1988 · 1.6K citations

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Surflex:  Fully Automatic Flexible Molecular Docking Using a Molecular Similarity-Based Search Engine

Ajay N. Jain · Journal of Medicinal Chemistry · 2003 · 1.4K citations

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Characterization of PicoGreen Reagent and Development of a Fluorescence-Based Solution Assay for Double-Stranded DNA Quantitation

Victoria L. Singer, Laurie J. Jones, Stephen Yue et al. · Analytical Biochemistry · 1997 · 783 citations

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Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

Rudi Pauwels, Koen Andries, Jan Desmyter et al. · Nature · 1990 · 757 citations

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