Concepedia

Vector Capsid Engineering

Vector Capsid Engineering is a specialized methodology within vector engineering that involves the rational design and modification of viral capsid proteins to enhance the safety, targeting specificity, and delivery efficiency of systemic gene delivery vectors.

49

Publications

2.5K

Citations

423

Authors

178

Institutions

Publications per year

2017–2026

33

Parents

Publications

49

Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity

Nicole K. Paulk, Katja Pekrun, Erhua Zhu et al. · Molecular Therapy · 2017 · 164 citations · Full text

, , +11

Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells

Ashley T. Martino, Etiena Basner‐Tschakarjan, David M. Markusic et al. · Blood · 2013 · 158 citations · Full text

, , +14

Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids

Michael J. Castle, Heikki Turunen, Luk H. Vandenberghe et al. · Methods in molecular biology · 2015 · 150 citations

, , +16

A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism

Marcus Davidsson, Gang Wang, Patrick Aldrin-Kirk et al. · Proceedings of the National Academy of Sciences · 2019 · 147 citations · Full text

, , +17

A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency

Julie Tordo, Claire O’Leary, André Saraiva Leão Marcelo Antunes et al. · Brain · 2018 · 127 citations · Full text

, , +15

1–5 of 49

Authors

423

  1. HB
    Hildegard Büning

    University of Cologne, Germany

    8 publications · 250 citations

    8

    h-index

  2. MA
    Mavis Agbandje‐McKenna

    University of Florida, United States

    4 publications · 297 citations

    4

    h-index

  3. FE
    Fatma-Elzahraa Eid

    Al-Azhar University, Egypt

    3 publications · 148 citations

    3

    h-index

  4. AT
    Albert T. Chen

    Broad Institute, United States

    3 publications · 148 citations

    3

    h-index

  5. IG
    Isabelle G. Tobey

    Broad Institute, United States

    3 publications · 148 citations

    3

    h-index

1–5 of 423

Institutions

178

  1. Inserm

    Paris, France

    9 h-index

    48 publications

    2K citations

  2. University of Florida

    Gainesville, United States

    8 h-index

    31 publications

    2K citations

  3. Medizinische Hochschule Hannover

    Hanover, Germany

    7 h-index

    45 publications

    1.4K citations

  4. University of Cologne

    Cologne, Germany

    4 h-index

    14 publications

    495 citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    11 publications

    243 citations

  6. University Hospital Cologne

    Cologne, Germany

    4 h-index

    11 publications

    428 citations

  7. Harvard University

    Cambridge, United States

    4 h-index

    5 publications

    463 citations

  8. Broad Institute

    Cambridge, United States

    3 h-index

    43 publications

    2.1K citations

1–8 of 178

Venues

  1. Human Gene Therapy

    6 publications · 153 citations

    6

    h-index

  2. 4

    h-index

  3. Gene Therapy

    4 publications · 178 citations

    4

    h-index

  4. Molecular Therapy

    4 publications · 355 citations

    4

    h-index

  5. Blood

    3 publications · 183 citations

    3

    h-index

1–5