Concepedia
Statistics
Publications
11
Citations
962
H-Index
10
Active since
2007
Affiliations
University of Pennsylvania(Current)
University of California San Diego
Children's Hospital of Philadelphia
United States Department of Veterans Affairs
Michael J. Castle is an author at University of Pennsylvania specializing in neuroscience, life sciences, and gene therapy.
Publications per year
2007–2025
Dosage Thresholds for AAV2 and AAV8 Photoreceptor Gene Therapy in Monkey
Luk H. Vandenberghe, Peter Bell, Albert M. Maguire et al. · Science Translational Medicine · 2011 · 232 citations
Medicine, Ophthalmology, Vision Science +17
Adeno-Associated Virus Serotypes 1, 8, and 9 Share Conserved Mechanisms for Anterograde and Retrograde Axonal Transport
Michael J. Castle, Zachary T. Gershenson, April R. Giles et al. · Human Gene Therapy · 2014 · 157 citations · Full text
Life Sciences, Neurobiology, Neuroscience +15
Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids
Michael J. Castle, Heikki Turunen, Luk H. Vandenberghe et al. · Methods in molecular biology · 2015 · 150 citations
Life Sciences, Molecular Biology, Neuroscience +16
Postmortem Analysis in a Clinical Trial of AAV2-NGF Gene Therapy for Alzheimer's Disease Identifies a Need for Improved Vector Delivery
Michael J. Castle, Fernando C. Baltanás, Imre Kovács et al. · Human Gene Therapy · 2020 · 117 citations · Full text
Medicine, Neurology, Neuroscience +17
Long-distance Axonal Transport of AAV9 Is Driven by Dynein and Kinesin-2 and Is Trafficked in a Highly Motile Rab7-positive Compartment
Michael J. Castle, Eran Perlson, Erika L.F. Holzbaur et al. · Molecular Therapy · 2013 · 93 citations · Full text
Life Sciences, Neurobiology, Neuroscience +17
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