April R. Giles

Adeno-Associated Virus Serotypes 1, 8, and 9 Share Conserved Mechanisms for Anterograde and Retrograde Axonal Transport

Michael J. Castle, Zachary T. Gershenson, April R. Giles et al. · Human Gene Therapy · 2014 · 153 citations · Full text

Serotype 8, Viral Replication, Molecular Biology +20

Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function

April R. Giles, Joshua J. Sims, Kevin B. Turner et al. · Molecular Therapy · 2018 · 113 citations · Full text

TLR9 signaling mediates adaptive immunity following systemic AAV gene therapy

Scott N. Ashley, Suryanarayan Somanathan, April R. Giles et al. · Cellular Immunology · 2019 · 61 citations · Full text

Autoimmune Disease, Adaptive Immune System, Immunology +7

Mapping an Adeno-associated Virus 9-Specific Neutralizing Epitope To Develop Next-Generation Gene Delivery Vectors

April R. Giles, L. Govindasamy, Suryanarayan Somanathan et al. · Journal of Virology · 2018 · 41 citations · Full text

Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors

Bradley S. Hollidge, Hayley B. Carroll, Randolph Qian et al. · Frontiers in Neurology · 2022 · 32 citations · Full text

Bilateral Injections, In Vivo Gene Therapy, Transgene Expression +22