Joshua J. Sims

BID Preferentially Activates BAK while BIM Preferentially Activates BAX, Affecting Chemotherapy Response

Kristopher A. Sarosiek, Xiaoke Chi, John A. Bachman et al. · Molecular Cell · 2013 · 237 citations · Full text

Medicine, Metronomic Therapy, Pharmacology +6

Linkage-Specific Avidity Defines the Lysine 63-Linked Polyubiquitin-Binding Preference of Rap80

Joshua J. Sims, Robert E. Cohen · Molecular Cell · 2009 · 219 citations · Full text

Protein Function, Protein Assembly, Natural Sciences +6

The GPI-Linked Protein LY6A Drives AAV-PHP.B Transport across the Blood-Brain Barrier

Juliette Hordeaux, Yuan Yuan, Peter Clark et al. · Molecular Therapy · 2019 · 216 citations · Full text

Fractional killing arises from cell‐to‐cell variability in overcoming a caspase activity threshold

Jérémie Roux, Marc Hafner, Samuel Bandara et al. · Molecular Systems Biology · 2015 · 144 citations · Full text

Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling

Joshua J. Sims, Francesco Scavone, Eric M. Cooper et al. · Nature Methods · 2012 · 125 citations

Protein Function, Signal Transduction, Signaling Pathway +8