Patrick Aldrin-Kirk

Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

Staffan Holmqvist, Oldriska Chutna, Luc Bousset et al. · Acta Neuropathologica · 2014 · 882 citations · Full text

Neuroanatomy, Experimental Neuropathology, Gastroenterology +10

Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

Pedro Rifes, Marc Isaksson, Gaurav Rathore et al. · Nature Biotechnology · 2020 · 219 citations · Full text

Neural Tube Development, Developmental Biology, Medicine +10

A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism

Marcus Davidsson, Gang Wang, Patrick Aldrin-Kirk et al. · Proceedings of the National Academy of Sciences · 2019 · 137 citations · Full text

Engineering, Synthetic Virology, Aav Capsid Surface +18

A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency

Julie Tordo, Claire O’Leary, André Saraiva Leão Marcelo Antunes et al. · Brain · 2018 · 123 citations · Full text

Virus Structure, Engineering, Molecular Virology +14

DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor

Patrick Aldrin-Kirk, Andreas Heuer, Gang Wang et al. · Neuron · 2016 · 61 citations · Full text