Concepedia

Type Ii Polyketide Synthases

Type II Polyketide Synthase is a bacterial iterative polyketide synthase system that functions as a discrete complex of monofunctional enzymes, distinguished from other polyketide synthases by its dissociated architecture and its role in synthesizing aromatic polyketides through repeated use of a minimal set of catalytic components.

260

Publications

15.9K

Citations

1.1K

Authors

329

Institutions

Publications per year

2017–2026

60

Variants

Type Ii Pks

Parents

Publications

260

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

Jesús Cortés, Stephen Haydock, Gareth A. Roberts et al. · Nature · 1990 · 631 citations

, , +13

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

Keishi Ishida, Holger Jenke‐Kodama, Elke Dittmann et al. · Nature Biotechnology · 2008 · 396 citations

, , +17

Chapter 17 Bacterial Fatty Acid Synthesis and its Relationships with Polyketide Synthetic Pathways

John E. Cronan, Jacob Thomas · Methods in enzymology on CD-ROM/Methods in enzymology · 2009 · 307 citations · Full text

, , +16

Structural control of polyketide formation in plant-specific polyketide synthases

Joseph M. Jez, M.B. Austin, M.E. Bowman et al. · Chemistry & Biology · 2000 · 272 citations · Full text

, , +14

Polyketide Synthase Gene Coupled to the Peptide Synthetase Module Involved in the Biosynthesis of the Cyclic Heptapeptide Microcystin

Tatsuo NISHIZAWA, Akiko Ueda, Munehiko Asayama et al. · The Journal of Biochemistry · 2000 · 260 citations

, , +9

1–5 of 260

Authors

1.1K

  1. CK
    Chaitan Khosla

    Stanford University, United States

    16 publications · 761 citations

    15

    h-index

  2. PF
    Peter F. Leadlay

    University of Cambridge, United Kingdom

    12 publications · 1.7K citations

    12

    h-index

  3. ST
    Shiou‐Chuan Tsai

    University of California, Irvine, United States

    11 publications · 510 citations

    11

    h-index

  4. JC
    John Crosby

    University of Bristol, United Kingdom

    11 publications · 484 citations

    11

    h-index

  5. CR
    C. Richard Hutchinson

    University of Wisconsin–Madison, United States

    11 publications · 898 citations

    11

    h-index

1–5 of 1.1K

Institutions

329

  1. Stanford University

    Stanford, United States

    14 h-index

    47 publications

    2.3K citations

  2. University of Bristol

    Bristol, United Kingdom

    13 h-index

    77 publications

    4.2K citations

  3. University of Cambridge

    Cambridge, United Kingdom

    13 h-index

    66 publications

    10.3K citations

  4. University of California, Irvine

    Irvine, United States

    12 h-index

    54 publications

    2.3K citations

  5. The University of Tokyo

    Tokyo, Japan

    11 h-index

    41 publications

    1.8K citations

  6. John Innes Centre

    Norwich, United Kingdom

    8 h-index

    26 publications

    3.3K citations

  7. University of California San Diego

    San Diego, United States

    8 h-index

    30 publications

    1.7K citations

  8. University of Wisconsin–Madison

    Madison, United States

    8 h-index

    30 publications

    2.4K citations

1–8 of 329

Venues

  1. Journal of the American Chemical Society

    JACS · 18 publications · 930 citations

    18

    h-index

  2. Chemistry & Biology

    19 publications · 1.7K citations

    18

    h-index

  3. Biochemistry

    12 publications · 606 citations

    12

    h-index

  4. ChemBioChem

    9 publications · 413 citations

    9

    h-index

  5. Gene

    9 publications · 1.2K citations

    9

    h-index

1–5