Shiou‐Chuan Tsai

Trapping the dynamic acyl carrier protein in fatty acid biosynthesis

Chi Nguyen, Robert W. Haushalter, D. John Lee et al. · Nature · 2013 · 264 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel

Shiou‐Chuan Tsai, Larry J. W. Miercke, J. Krucinski et al. · Proceedings of the National Academy of Sciences · 2001 · 214 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization

Jason M. Crawford, Tyler P. Korman, Jason W. Labonte et al. · Nature · 2009 · 181 citations · Full text

Engineering, Biotechnology, Bioorganic Chemistry +15

Catalysis, Specificity, and ACP Docking Site of Streptomyces coelicolor Malonyl-CoA:ACP Transacylase

Adrian T. Keatinge‐Clay, Anang A. Shelat, David F. Savage et al. · Structure · 2003 · 137 citations · Full text

Life Sciences, Biochemistry, Microbiology +16

Insights into Channel Architecture and Substrate Specificity from Crystal Structures of Two Macrocycle-Forming Thioesterases of Modular Polyketide Synthases^,

Shiou‐Chuan Tsai, Hongxiang Lu, David E. Cane et al. · Biochemistry · 2002 · 123 citations

Life Sciences, Biochemistry, Molecular Biology +16