Peter F. Leadlay

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

Jesús Cortés, Stephen Haydock, Gareth A. Roberts et al. · Nature · 1990 · 631 citations

Life Sciences, Biochemistry, Enzyme Mechanism +13

How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 å resolution

Filippo Mancia, N.H. Keep, Atsushi Nakagawa et al. · Structure · 1996 · 464 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338

Markiyan Oliynyk, Markiyan Samborskyy, J B Lester et al. · Nature Biotechnology · 2007 · 410 citations · Full text

Life Sciences, Genetics, Microbiology +17

Giant plasmid-encoded polyketide synthases produce the macrolide toxin of <i>Mycobacterium ulcerans</i>

Timothy P. Stinear, Armand Mve-Obiang, Pamela L. C. Small et al. · Proceedings of the National Academy of Sciences · 2004 · 381 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

A chain initiation factor common to both modular and aromatic polyketide synthases

Christian Bisang, Paul F. Long, James Westcott et al. · Nature · 1999 · 279 citations

Pharmacy, Biochemistry, Molecular Biology +10