The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.

Torsten Schwecke, Jesús F. Aparicio, István Molnár, +7

Proceedings of the National Academy of Sciences

Systems BiologyBiosynthesisEngineeringCellular EnzymologyNatural Sciences +12

Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338

Markiyan Oliynyk, Markiyan Samborskyy, J B Lester, +5

Nature Biotechnology

BacteriologyMolecular BiologyGenomicsSecondary MetabolitesDrug Resistance +14

Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes

Patrick Caffrey, Susan V. Lynch, Elizabeth M. Flood, +2

Chemistry & Biology

Amphotericin BiosynthesisLate GenesBiosynthesisEngineeringBiotransformation +5

A hybrid modular polyketide synthase obtained by domain swapping

Markiyan Oliynyk, Murray J. B. Brown, Jesús Cortés, +2

Chemistry & Biology

BiosynthesisEngineeringNatural SciencesBiocatalysisSynthetic Biology +4

Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in <i>Streptomyces cinnamonensis</i> and evidence for the role of <i>monB</i> and <i>monC</i> genes in oxidative cyclization

Markiyan Oliynyk, Christian B. W. Stark, Apoorva Bhatt, +7

Molecular Microbiology

Biosynthesis of the Angiogenesis Inhibitor Borrelidin by Streptomyces parvulus Tü4055

Carlos Olano, Barrie Wilkinson, César Sánchez, +10

Chemistry & Biology

BiosynthesisAngiogenesis Inhibitor BorrelidinMedicineNatural Product BiosynthesisMicrobiology +3

Identification of a Phosphopantetheinyl Transferase for Erythromycin Biosynthesis in <i>Saccharopolyspora erythraea</i>

Kira J. Weissman, Hui Hong, Markiyan Oliynyk, +1

ChemBioChem

A New Modular Polyketide Synthase in the Erythromycin Producer &lt;i&gt;Saccharopolyspora erythraea&lt;/i&gt;

Steven Boakes, Markiyan Oliynyk, Jesús Cortés, +5

Microbial Physiology

Actinomycete integrative and conjugative pMEA-like elements of Amycolatopsis and Saccharopolyspora decoded

Evelien M. te Poele, Markiyan Samborskyy, Markiyan Oliynyk, +3

Plasmid

BiosynthesisBiotransformationBiochemistryBiochemical TaxonomySlime Mould +4

Amphotericin Biosynthesis in Streptomyces nodosus

Patrick Caffrey, Susan V. Lynch, Elizabeth M. Flood, +2

Chemistry & Biology

Amphotericin BiosynthesisBiosynthesisBioorganic ChemistryBiotransformationBiochemistry +3