Jesús F. Aparicio

The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.

Torsten Schwecke, Jesús F. Aparicio, István Molnár et al. · Proceedings of the National Academy of Sciences · 1995 · 447 citations · Full text

Systems Biology, Biosynthesis, Engineering +14

Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: Analysis of the enzymatic domains in the modular polyketide synthase

Jesús F. Aparicio, István Molnár, Torsten Schwecke et al. · Gene · 1996 · 242 citations

Biosynthesis, Engineering, Cellular Enzymology +9

Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl‐CoA:acyl carrier protein transacylase domains in modular polyketide synthases

Stephen Haydock, Jesús F. Aparicio, István Molnár et al. · FEBS Letters · 1995 · 241 citations · Full text

Engineering, Molecular Biology, Escherichia Coli +16

Stereospecific Acyl Transfers on the Erythromycin-Producing Polyketide Synthase

Andrew F. A. Marsden, Patrick Caffrey, Jesús F. Aparicio et al. · Science · 1994 · 164 citations

The two-component phoR-phoP system of Streptomyces natalensis: Inactivation or deletion of phoP reduces the negative phosphate regulation of pimaricin biosynthesis

Marta V. Mendes, Sedef Tunca, Nuria Antón et al. · Metabolic Engineering · 2006 · 150 citations

Biosynthesis, Two-component Phor-phop System, Engineering +9