C. Richard Hutchinson

Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis

Jonathan Kennedy, Karine Auclair, Steven G. Kendrew et al. · Science · 1999 · 659 citations

Engineering, Polyketide Synthase Activity, Molecular Biology +18

Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699

Paul R. August, Li Tang, Yeo Joon Yoon et al. · Chemistry & Biology · 1998 · 348 citations · Full text

Biosynthesis, Engineering, Biotransformation +10

A Model of Structure and Catalysis for Ketoreductase Domains in Modular Polyketide Synthases

Ralph Reid, Misty Piagentini, Eduardo Rodrı́guez et al. · Biochemistry · 2002 · 308 citations

Biosynthesis, Biotin Recognition Sequence, Engineering +15

Cloning of genes governing the deoxysugar portion of the erythromycin biosynthesis pathway in Saccharopolyspora erythraea (Streptomyces erythreus)

Jesús Vara, Marlena Lewandowska-Skarbek, Y G Wang et al. · Journal of Bacteriology · 1989 · 287 citations · Full text

Deoxysugar Portion, Genetics, Bacteriology +22

Metagenomic Analysis Reveals Diverse Polyketide Synthase Gene Clusters in Microorganisms Associated with the Marine Sponge <i>Discodermia dissoluta</i>

Andreas Schirmer, Rishali Gadkari, Christopher D. Reeves et al. · Applied and Environmental Microbiology · 2005 · 272 citations · Full text