Concepedia

Type I Polyketide Synthases

Type I Polyketide Synthases is a modular multi-enzyme complex that synthesizes polyketides through an assembly-line mechanism in which catalytic domains are covalently linked within a single polypeptide chain, distinguishing it from dissociated Type II systems.

180

Publications

12.4K

Citations

830

Authors

267

Institutions

Publications per year

2017–2026

43

Variants

Type I Pks

Parents

Publications

180

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

Jesús Cortés, Stephen Haydock, Gareth A. Roberts et al. · Nature · 1990 · 631 citations

, , +13

Insights from the complete genome sequence of <i>Mycobacterium marinum</i> on the evolution of <i>Mycobacterium tuberculosis</i>

Timothy P. Stinear, Torsten Seemann, Paul F. Harrison et al. · Genome Research · 2008 · 564 citations · Full text

, , +12

Phylogenomic analysis of type I polyketide synthase genes in pathogenic and saprobic ascomycetes

Scott Kroken, N. Louise Glass, John W. Taylor et al. · Proceedings of the National Academy of Sciences · 2003 · 523 citations · Full text

, , +17

Giant plasmid-encoded polyketide synthases produce the macrolide toxin of <i>Mycobacterium ulcerans</i>

Timothy P. Stinear, Armand Mve-Obiang, Pamela L. C. Small et al. · Proceedings of the National Academy of Sciences · 2004 · 381 citations · Full text

, , +17

Metagenomic Analysis Reveals Diverse Polyketide Synthase Gene Clusters in Microorganisms Associated with the Marine Sponge <i>Discodermia dissoluta</i>

Andreas Schirmer, Rishali Gadkari, Christopher D. Reeves et al. · Applied and Environmental Microbiology · 2005 · 272 citations

, , +14

1–5 of 180

Authors

830

  1. JD
    Jay D. Keasling

    University of California, Berkeley, United States

    10 publications · 452 citations

    10

    h-index

  2. PF
    Peter F. Leadlay

    University of Cambridge, United Kingdom

    10 publications · 1.5K citations

    10

    h-index

  3. LK
    Leonard Katz

    Abbott Fund, United States

    9 publications · 447 citations

    9

    h-index

  4. CK
    Chaitan Khosla

    Stanford University, United States

    8 publications · 351 citations

    8

    h-index

  5. SY
    Satoshi Yuzawa

    Joint BioEnergy Institute, United States

    7 publications · 336 citations

    7

    h-index

1–5 of 830

Institutions

267

  1. University of California, Berkeley

    Berkeley, United States

    11 h-index

    40 publications

    3.7K citations

  2. The University of Tokyo

    Tokyo, Japan

    10 h-index

    31 publications

    2.5K citations

  3. Joint BioEnergy Institute

    Emeryville, United States

    10 h-index

    69 publications

    3.1K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    10 h-index

    56 publications

    7K citations

  5. Stanford University

    Stanford, United States

    9 h-index

    25 publications

    1.2K citations

  6. Lawrence Berkeley National Laboratory

    Berkeley, United States

    9 h-index

    54 publications

    2.2K citations

  7. Technical University of Denmark

    Kongens Lyngby, Denmark

    8 h-index

    8 publications

    409 citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    53 publications

    2.6K citations

1–8 of 267

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 1.6K citations

    10

    h-index

  2. Chemistry & Biology

    8 publications · 898 citations

    8

    h-index

  3. ChemBioChem

    7 publications · 289 citations

    7

    h-index

  4. ACS Chemical Biology

    6 publications · 243 citations

    6

    h-index

  5. Journal of the American Chemical Society

    JACS · 6 publications · 295 citations

    6

    h-index

1–5