Concepedia

Thymic Education

Thymic Education is a theoretical construct in immunology that delineates the process by which developing T cells undergo central tolerance in the thymus, distinguished by the context-specific elimination or regulation of self-reactive T cell clones to establish self-tolerance.

32

Publications

2K

Citations

175

Authors

71

Institutions

Publications per year

2017–2026

2

Variants

Thymic Selection

Parents

Publications

32

Suppressor T cells.

Richard K. Gershon, Philip L. Cohen, Ronald S. Hencin et al. · PubMed · 1972 · 427 citations

, , +9

Suppressor T Cells

Richard K. Gershon, Philip P. Cohen, Ronald S. Hencin et al. · The Journal of Immunology · 1972 · 295 citations · Full text

, , +8

Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: potential model for thymic education.

Virginia Godfrey, John E. Wilkinson, Eugene M. Rinchik et al. · Proceedings of the National Academy of Sciences · 1991 · 178 citations

, , +17

An essential role for gp39, the ligand for CD40, in thymic selection.

Teresa M. Foy, Dawne M. Page, Thomas J. Waldschmidt et al. · The Journal of Experimental Medicine · 1995 · 146 citations · Full text

, , +17

Degenerate recognition of a dissimilar antigenic peptide by myelin basic protein-reactive T cells. Implications for thymic education and autoimmunity.

V Bhardwaj, Vipin Kumar, H. Mario Geysen et al. · The Journal of Immunology · 1993 · 142 citations · Full text

, , +17

1–5 of 32

Authors

175

  1. ML
    Marco Londei

    Charing Cross Hospital, United Kingdom

    2 publications · 86 citations

    2

    h-index

  2. RK
    Richard K. Gershon

    Yale University, United States

    2 publications · 722 citations

    2

    h-index

  3. RS
    Ronald S. Hencin

    Yale University, United States

    2 publications · 722 citations

    2

    h-index

  4. SQ
    Sonia Quaratino

    University of Southampton, United Kingdom

    2 publications · 86 citations

    2

    h-index

  5. SA
    Stephen A. Liebhaber

    University of Pennsylvania, United States

    2 publications · 722 citations

    2

    h-index

1–5 of 175

Institutions

71

  1. National Institutes of Health

    Bethesda, United States

    3 h-index

    8 publications

    209 citations

  2. National Cancer Institute

    Bethesda, United States

    3 h-index

    8 publications

    209 citations

  3. Massachusetts General Hospital

    Boston, United States

    2 h-index

    20 publications

    546 citations

  4. Université Paris Cité

    Paris, France

    2 h-index

    4 publications

    56 citations

  5. Harvard University

    Cambridge, United States

    2 h-index

    20 publications

    546 citations

  6. Yale University

    New Haven, United States

    2 h-index

    5 publications

    1.2K citations

  7. Inserm

    Paris, France

    2 h-index

    3 publications

    52 citations

  8. Institut Cochin

    Paris, France

    1 h-index

    2 publications

    26 citations

1–8 of 71

Venues

  1. The Journal of Immunology

    JI · 10 publications · 624 citations

    10

    h-index

  2. The Journal of Experimental Medicine

    7 publications · 404 citations

    7

    h-index

  3. PubMed

    Repository · 5 publications · 599 citations

    5

    h-index

  4. European Journal of Immunology

    EJI · 4 publications · 87 citations

    4

    h-index

  5. Biology of Blood and Marrow Transplantation

    TCT · 1 publications · 49 citations

    1

    h-index

1–5