Suppressor T cells.

Abstract

The antigen-induced DNA synthetic response of a number of different thymocyte populations was studied in the spleens of lethally irradiated recipients by incorporation of 125 I 5-iodo-2-deoxyuridine. The response of certain cell combinations was not only less than the sum of the two responding alone but less than one of the individual cell populations in the combination. The following combinations had this effect: 1) “Educated” and normal thymocytes 1 thymocytes 1 hosts; 3) cortisone resistant (in a low dose) and normal thymocytes