Concepedia

Tau Propagation

Tau Propagation is a pathological process in which misfolded tau protein spreads in a prion-like, neuron-to-neuron manner across anatomically connected brain regions, thereby facilitating the progressive dissemination of tauopathy in neurodegenerative diseases such as Alzheimer’s disease.

215

Publications

30.2K

Citations

2K

Authors

491

Institutions

Publications per year

2017–2026

163

Variants

Tau Spreading

Parents

Publications

215

Transmission and spreading of tauopathy in transgenic mouse brain

Florence Clavaguera, Tristan Bolmont, R. Anthony Crowther et al. · Nature Cell Biology · 2009 · 1.8K citations · Full text

, , +12

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

Hirohide Asai, Seiko Ikezu, Satoshi Tsunoda et al. · Nature Neuroscience · 2015 · 1.6K citations

, , +12

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

Alix de Calignon, Manuela Polydoro, Marc Suárez‐Calvet et al. · Neuron · 2012 · 1.4K citations · Full text

, , +14

Propagation of Tau Misfolding from the Outside to the Inside of a Cell

Bess Frost, Rachel Lauren Jacks, Marc I. Diamond · Journal of Biological Chemistry · 2009 · 1.3K citations · Full text

, , +17

Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies

David W. Sanders, Sarah K. Kaufman, Sarah L. DeVos et al. · Neuron · 2014 · 1K citations · Full text

, , +14

1–5 of 215

Authors

2K

  1. MI
    Marc I. Diamond

    The University of Texas Southwestern Medical Center, United States

    14 publications · 5.3K citations

    14

    h-index

  2. BT
    Bradley T. Hyman

    Massachusetts General Hospital, United States

    15 publications · 3.4K citations

    14

    h-index

  3. JQ
    John Q. Trojanowski

    University of Pennsylvania, United States

    11 publications · 2.6K citations

    11

    h-index

  4. VM
    Virginia M.‐Y. Lee

    University of Pennsylvania, United States

    11 publications · 3.1K citations

    11

    h-index

  5. SW
    Susanne Wegmann

    Massachusetts General Hospital, United States

    10 publications · 1.7K citations

    10

    h-index

1–5 of 2K

Institutions

491

  1. Harvard University

    Cambridge, United States

    25 h-index

    187 publications

    32.5K citations

  2. Massachusetts General Hospital

    Boston, United States

    21 h-index

    190 publications

    32.7K citations

  3. University of California, San Francisco

    San Francisco, United States

    17 h-index

    124 publications

    22.5K citations

  4. University of Pennsylvania

    Philadelphia, United States

    16 h-index

    122 publications

    31.1K citations

  5. German Center for Neurodegenerative Diseases

    Bonn, Germany

    16 h-index

    65 publications

    15.2K citations

  6. Washington University in St. Louis

    St Louis, United States

    15 h-index

    103 publications

    28.7K citations

  7. Boston University

    Boston, United States

    13 h-index

    68 publications

    23.6K citations

  8. Institute on Aging

    San Francisco, United States

    12 h-index

    81 publications

    18.5K citations

1–8 of 491

Venues

  1. Acta Neuropathologica

    12 publications · 2.2K citations

    12

    h-index

  2. Acta Neuropathologica Communications

    11 publications · 1.2K citations

    11

    h-index

  3. Brain

    10 publications · 1.3K citations

    10

    h-index

  4. Journal of Biological Chemistry

    JBC · 10 publications · 2.9K citations

    10

    h-index

  5. Journal of Alzheimer s Disease

    JAD · 8 publications · 246 citations

    8

    h-index

1–5