Concepedia

Subclonal Architecture Analysis

Subclonal Architecture Analysis is a computational and analytical framework within single-cell genomics that reconstructs the evolutionary lineage and clonal heterogeneity of tumor cells by resolving the phylogenetic relationships and mutational dynamics among subpopulations from single-cell DNA sequencing data.

46

Publications

5.1K

Citations

667

Authors

215

Institutions

Publications per year

2017–2026

37

Parents

Publications

46

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

Lucy Yates, Moritz Gerstung, Stian Knappskog et al. · Nature Medicine · 2015 · 840 citations · Full text

, , +16

SciClone: Inferring Clonal Architecture and Tracking the Spatial and Temporal Patterns of Tumor Evolution

Christopher A. Miller, Brian S. White, Nathan D. Dees et al. · PLoS Computational Biology · 2014 · 495 citations · Full text

, , +17

TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data

Gavin Ha, Andrew Roth, Jaswinder Khattra et al. · Genome Research · 2014 · 429 citations · Full text

, , +17

MuSE: accounting for tumor heterogeneity using a sample-specific error model improves sensitivity and specificity in mutation calling from sequencing data

Yu Fan, Xi Liu, Daniel Hughes et al. · Genome biology · 2016 · 310 citations · Full text

, , +17

Quantification of subclonal selection in cancer from bulk sequencing data

Marc Williams, Benjamin Werner, Timon Heide et al. · Nature Genetics · 2018 · 298 citations

, , +12

1–5 of 46

Authors

667

  1. PJ
    Peter J. Campbell

    Wellcome Sanger Institute, United Kingdom

    4 publications · 1.3K citations

    4

    h-index

  2. JZ
    Jianjun Zhang

    The University of Texas MD Anderson Cancer Center, United States

    4 publications · 603 citations

    3

    h-index

  3. TJ
    Timothy J. Ley

    Washington University in St. Louis, United States

    3 publications · 793 citations

    3

    h-index

  4. CA
    Christopher A. Miller

    Washington University in St. Louis, United States

    3 publications · 793 citations

    3

    h-index

  5. HG
    Hartmut Goldschmidt

    Heidelberg University, Germany

    2 publications · 98 citations

    2

    h-index

1–5 of 667

Institutions

215

  1. Wellcome Sanger Institute

    Cambridge, United Kingdom

    7 h-index

    46 publications

    21.9K citations

  2. German Cancer Research Center

    Heidelberg, Germany

    5 h-index

    66 publications

    3.4K citations

  3. Heidelberg University

    Heidelberg, Germany

    5 h-index

    94 publications

    4.4K citations

  4. Harvard University

    Cambridge, United States

    5 h-index

    24 publications

    3.8K citations

  5. Stanford University

    Stanford, United States

    4 h-index

    20 publications

    1.5K citations

  6. University Hospital Heidelberg

    Heidelberg, Germany

    4 h-index

    46 publications

    1.8K citations

  7. Massachusetts General Hospital

    Boston, United States

    3 h-index

    4 publications

    735 citations

  8. The University of Texas MD Anderson Cancer Center

    Houston, United States

    3 h-index

    27 publications

    4.4K citations

1–8 of 215

Venues

  1. Nature Communications

    8 publications · 820 citations

    8

    h-index

  2. Leukemia

    3 publications · 188 citations

    3

    h-index

  3. Genome Research

    GR · 3 publications · 807 citations

    3

    h-index

  4. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 3 publications · 67 citations

    3

    h-index

  5. Clinical Cancer Research

    2 publications · 185 citations

    2

    h-index

1–5