Concepedia

Single-cell Pathway Modeling

Single-Cell Pathway Modeling is a computational framework that reconstructs and quantifies the activity of biological pathways at the individual cell level by integrating single-cell omics data with prior knowledge of gene regulatory or metabolic networks.

15

Publications

2.4K

Citations

142

Authors

56

Institutions

Publications per year

2017–2026

11

Parents

Publications

15

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

Lei Zhang, Ziyi Li, Katarzyna M. Skrzypczynska et al. · Cell · 2020 · 1.6K citations · Full text

, , +16

Systematic single-cell pathway analysis to characterize early T cell activation

Jack Bibby, Divyansh Agarwal, Tilo Freiwald et al. · Cell Reports · 2022 · 156 citations · Full text

, , +14

CytoTalk: De novo construction of signal transduction networks using single-cell transcriptomic data

Yuxuan Hu, Tao Peng, Lin Gao et al. · Science Advances · 2021 · 144 citations · Full text

, , +17

Exploring Metabolic Configurations of Single Cells within Complex Tissue Microenvironments

Anne Miller, Csörsz Nagy, Bernhard Knapp et al. · Cell Metabolism · 2017 · 114 citations · Full text

, , +16

Bacterial sugar utilization gives rise to distinct single‐cell behaviours

Taliman Afroz, Konstantinos Biliouris, Yiannis N. Kaznessis et al. · Molecular Microbiology · 2014 · 66 citations · Full text

, , +16

1–5 of 15

Authors

142

  1. DW
    Daniel Woschée

    Center for NanoScience, Germany

    2 publications · 44 citations

    2

    h-index

  2. FF
    Fabian Fröhlich

    Technical University of Munich, Germany

    2 publications · 44 citations

    2

    h-index

  3. JO
    Joachim O. Rädler

    Ludwig-Maximilians-Universität München, Germany

    2 publications · 44 citations

    2

    h-index

  4. TL
    Thomas Ligon

    Center for NanoScience, Germany

    2 publications · 44 citations

    2

    h-index

  5. JH
    Jan Hasenauer

    Helmholtz Zentrum München, Germany

    2 publications · 44 citations

    2

    h-index

1–5 of 142

Institutions

56

  1. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    6 publications

    396 citations

  2. Center for NanoScience

    Munich, Germany

    2 h-index

    10 publications

    220 citations

  3. Helmholtz Zentrum München

    Munich, Germany

    2 h-index

    6 publications

    132 citations

  4. Ludwig-Maximilians-Universität München

    Munich, Germany

    2 h-index

    10 publications

    220 citations

  5. Technical University of Munich

    Munich, Germany

    2 h-index

    6 publications

    132 citations

  6. University of Bonn

    Bonn, Germany

    2 h-index

    2 publications

    52 citations

  7. Oregon Health & Science University

    Portland, United States

    2 h-index

    13 publications

    318 citations

  8. Comprehensive Cancer Center Vienna

    Vienna, Austria

    1 h-index

    2 publications

    228 citations

1–8 of 56

Venues

  1. Molecular Systems Biology

    1 publications · 24 citations

    1

    h-index

  2. Nucleic Acids Research

    1 publications · 24 citations

    1

    h-index

  3. Scientific Reports

    1 publications · 23 citations

    1

    h-index

  4. Science Advances

    1 publications · 144 citations

    1

    h-index

  5. npj Systems Biology and Applications

    1 publications · 33 citations

    1

    h-index

1–5