Lei Zhang

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

Lei Zhang, Ziyi Li, Katarzyna M. Skrzypczynska et al. · Cell · 2020 · 1.6K citations · Full text

Medicine, Cell Biology, Oncology +16

METTL3-mediated m6A modification of ATG7 regulates autophagy-GATA4 axis to promote cellular senescence and osteoarthritis progression

Xiang Chen, Wang Gong, Xiaoyan Shao et al. · Annals of the Rheumatic Diseases · 2021 · 350 citations

Medicine, Cell Biology, Orthopaedic Surgery +17

CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers

Bo Huang, Lei Zhang, Jie Zhao et al. · Cancer Letters · 2007 · 345 citations

Medicine, Cancer Biology, Oncology +14

SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment

Bo Huang, Lei Zhang, Guimei Zhang et al. · Blood · 2008 · 344 citations · Full text

Medicine, Immunology, Oncology +14

The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination

Bingyu Liu, Meng Zhang, Honglei Chu et al. · Nature Immunology · 2016 · 335 citations

Life Sciences, Cell Biology, Molecular Biology +12