Concepedia

Replisome Assembly

Replisome Assembly is the precisely coordinated process by which the multiprotein complex responsible for DNA replication is sequentially and spatially organized at a replication origin, distinguishing it from other DNA transaction complexes through its specific recruitment of helicase, primase, and polymerase activities to initiate bidirectional DNA synthesis.

230

Publications

18.1K

Citations

896

Authors

290

Institutions

Publications per year

2017–2026

84

Parents

Children

Publications

230

GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks

Agnieszka Gambus, Richard C. Jones, Alberto Sánchez‐Díaz et al. · Nature Cell Biology · 2006 · 766 citations

, , +14

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

Cécile Evrin, Pippa Clarke, Juergen Zech et al. · Proceedings of the National Academy of Sciences · 2009 · 551 citations

, , +17

Cep97 and CP110 Suppress a Cilia Assembly Program

Alexander Spektor, William Y.W. Tsang, David Khoo et al. · Cell · 2007 · 487 citations · Full text

, , +5

Visualization of replication factories attached to a nucleoskeleton

Pavel Hozák, A. Bassim Hassan, Dean A. Jackson et al. · Cell · 1993 · 469 citations

, , +12

Reconstitution of a minimal mtDNA replisome in vitro

Jenny Korhonen, Xuan Hoi Pham, Mina Pellegrini et al. · The EMBO Journal · 2004 · 398 citations · Full text

, , +12

1–5 of 230

Authors

896

  1. KL
    Karim Labib

    MRC Protein Phosphorylation and Ubiquitylation Unit, United Kingdom

    16 publications · 2.5K citations

    15

    h-index

  2. SJ
    Stephen J. Benkovic

    Pennsylvania State University, United States

    12 publications · 533 citations

    11

    h-index

  3. MO
    Mike O’Donnell

    Howard Hughes Medical Institute, United States

    10 publications · 1.3K citations

    10

    h-index

  4. JT
    Joseph T.P. Yeeles

    MRC Laboratory of Molecular Biology, United Kingdom

    7 publications · 1.2K citations

    7

    h-index

  5. CC
    Charles C. Richardson

    Harvard University, United States

    7 publications · 446 citations

    7

    h-index

1–5 of 896

Institutions

290

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    18 h-index

    49 publications

    6.4K citations

  2. Harvard University

    Cambridge, United States

    14 h-index

    58 publications

    4.4K citations

  3. Rockefeller University

    New York, United States

    12 h-index

    47 publications

    6.2K citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    11 h-index

    28 publications

    2.3K citations

  5. MRC Protein Phosphorylation and Ubiquitylation Unit

    Dundee, United Kingdom

    11 h-index

    37 publications

    2.6K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    60 publications

    1.9K citations

  7. Pennsylvania State University

    State College, United States

    11 h-index

    53 publications

    2K citations

  8. University of Dundee

    Dundee, United Kingdom

    10 h-index

    38 publications

    2.8K citations

1–8 of 290

Venues

  1. Journal of Biological Chemistry

    JBC · 23 publications · 858 citations

    19

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 21 publications · 2.2K citations

    19

    h-index

  3. Molecular Cell

    17 publications · 2.4K citations

    16

    h-index

  4. Nucleic Acids Research

    21 publications · 917 citations

    15

    h-index

  5. Nature Communications

    13 publications · 724 citations

    13

    h-index

1–5