Concepedia

Clamp Loader Complexes

Clamp Loader Complexes is a multisubunit protein complex that, as a component of the replisome, functions to recognize primer-template junctions and catalyze the ATP-dependent loading of sliding clamps onto DNA to enable processive DNA synthesis during replication in both prokaryotes and plants.

110

Publications

9.5K

Citations

367

Authors

140

Institutions

Publications per year

2017–2026

13

Variants

Clamp Loaders

Parents

Publications

110

AAA<sup>+</sup>: A Class of Chaperone-Like ATPases Associated with the Assembly, Operation, and Disassembly of Protein Complexes

Andrew F. Neuwald, L. Aravind, John L. Spouge et al. · Genome Research · 1999 · 1.8K citations · Full text

, , +17

Structural analysis of a eukaryotic sliding DNA clamp–clamp loader complex

Gregory D. Bowman, Mike O’Donnell, John Kuriyan · Nature · 2004 · 460 citations

, , +12

Stoichiometry and Architecture of Active DNA Replication Machinery in <i>Escherichia coli</i>

Rodrigo Reyes‐Lamothe, David J. Sherratt, Mark C. Leake · Science · 2010 · 417 citations · Full text

, , +17

Biochemical Characterization of DNA Damage Checkpoint Complexes: Clamp Loader and Clamp Complexes with Specificity for 5′ Recessed DNA

Viola Ellison, Bruce Stillman · PLoS Biology · 2003 · 364 citations · Full text

, , +17

Crystal Structure of the Processivity Clamp Loader Gamma (γ) Complex of E. coli DNA Polymerase III

David Jeruzalmi, Mike O’Donnell, John Kuriyan · Cell · 2001 · 318 citations · Full text

, , +16

1–5 of 110

Authors

367

  1. MO
    Mike O’Donnell

    Howard Hughes Medical Institute, United States

    28 publications · 2.9K citations

    24

    h-index

  2. JK
    John Kuriyan

    Howard Hughes Medical Institute, United States

    13 publications · 2K citations

    13

    h-index

  3. SJ
    Stephen J. Benkovic

    Pennsylvania State University, United States

    10 publications · 444 citations

    10

    h-index

  4. CS
    Charles S. McHenry

    University of Colorado Health, United States

    5 publications · 143 citations

    5

    h-index

  5. GD
    Gregory D. Bowman

    Johns Hopkins University, United States

    5 publications · 762 citations

    5

    h-index

1–5 of 367

Institutions

140

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    25 h-index

    94 publications

    11K citations

  2. Rockefeller University

    New York, United States

    23 h-index

    77 publications

    7.8K citations

  3. University of California, Berkeley

    Berkeley, United States

    11 h-index

    35 publications

    4.4K citations

  4. Pennsylvania State University

    State College, United States

    9 h-index

    31 publications

    1.2K citations

  5. Lawrence Berkeley National Laboratory

    Berkeley, United States

    9 h-index

    22 publications

    2K citations

  6. Cornell University

    Ithaca, United States

    5 h-index

    16 publications

    2K citations

  7. Cold Spring Harbor Laboratory

    Cold Spring Harbor, United States

    5 h-index

    13 publications

    8.4K citations

  8. University of Florida

    Gainesville, United States

    5 h-index

    21 publications

    886 citations

1–8 of 140

Venues

  1. Journal of Biological Chemistry

    JBC · 24 publications · 1.2K citations

    20

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 734 citations

    10

    h-index

  3. Nucleic Acids Research

    10 publications · 314 citations

    10

    h-index

  4. eLife

    6 publications · 461 citations

    6

    h-index

  5. Cell

    5 publications · 1.2K citations

    5

    h-index

1–5