A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

Cécile Evrin, Pippa Clarke, Juergen Zech, +6

Proceedings of the National Academy of Sciences

Double-hexameric Mcm2-7 ComplexProtein AssemblyGeneticsDna AnalysisMolecular Biology +14

A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome

Aline C. Simon, Rajika L. Perera, Frederick van Deursen, +8

Nature

ChromatinNucleic Acid ChemistryMedicineNatural SciencesCmg Helicase +7

Eukaryotic Replisome Components Cooperate to Process Histones During Chromosome Replication

Magdalena Foltman, Cécile Evrin, Giacomo De Piccoli, +6

Cell Reports

Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA

Jingchuan Sun, Cécile Evrin, Stefan A. Samel, +6

Nature Structural & Molecular Biology

Nucleic Acid ChemistryProtein AssemblyNatural SciencesMedicineNucleic Acid Biochemistry +7

An ORC/Cdc6/MCM2-7 Complex Is Formed in a Multistep Reaction to Serve as a Platform for MCM Double-Hexamer Assembly

Alejandra Fernandez‐Cid, Alberto Riera, Silvia Tognetti, +7

Molecular Cell

Supramolecular AssemblyMultistep ReactionNatural SciencesSelf-assemblyMolecular Self-assembly +7

Histone H2A‐H2B binding by Pol α in the eukaryotic replisome contributes to the maintenance of repressive chromatin

Cécile Evrin, Joseph D Maman, Aurora Diamante, +2

The EMBO Journal

Structure of Escherichia coli UMP Kinase Differs from That ofOther Nucleoside Monophosphate Kinases and Sheds New Light on EnzymeRegulation

Pierre Briozzo, Cécile Evrin, Philippe Meyer, +4

Journal of Biological Chemistry

BiosynthesisCellular EnzymologyBiochemistryProtein AssemblyProtein Folding +12

In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization

Cécile Evrin, Alejandra Fernandez‐Cid, J. Zech, +6

Nucleic Acids Research

Structural and Functional Characterization of Escherichia coli UMP Kinase in Complex with Its Allosteric Regulator GTP

Philippe Meyer, Cécile Evrin, Pierre Briozzo, +3

Journal of Biological Chemistry

Protein AssemblyBiomolecular Structure PredictionStructural BioinformaticsTighter Dimer-dimer InteractionMolecular Biology +16

The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation

Cécile Evrin, Alejandra Fernandez‐Cid, Alberto Riera, +6

Nucleic Acids Research